This book by Michael Brooks was mostly enjoyable reading. I agree wholeheartedly with the motivating Kuhnian philosophy of this book which states that anomalies are usually the gateways to significant advances in scientific understanding.
My favourite chapter was the first, on the problems of dark matter and dark energy–I think he’s right that a resolution may come when we apply general relativity without the simplifying assumption of isotropy.
As for the other chapters: discussion of the Pioneer Anomaly is now redundant and I think that homeopathy is too much pseudo-science to warrant it a chapter to itself, although that only means that Brooks failed to convince me otherwise, not that I’m right. The remaining chapters were uniformly good.